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[一名HIV血清阴性男性因潜伏感染内源性再激活导致的播散性组织胞浆菌病]

[Generalized histoplasmosis due to endogenous reactivation of a latent infection in an HIV-seronegative man].

作者信息

Koot R A, van Uum S H, Naber A H, Meis J F

机构信息

Afd. Pathologie, Academisch Ziekenhuis, Nijmegen.

出版信息

Ned Tijdschr Geneeskd. 1995 Jul 15;139(28):1454-6.

PMID:7623932
Abstract

A 63-year-old, Dutch, HIV-seronegative man presented with anal pain and itch of 6 months' duration, a perianal ulcer and a solitary colon ulcer. Crohn's disease was suspected; the patient was treated with corticosteroids, but later died. Autopsy revealed disseminated histoplasmosis, a fungal disease rare in the Netherlands. The patient had visited Honduras. This case report illustrates that disseminated histoplasmosis may mimic Crohn's disease leading to a delay in the diagnosis.

摘要

一名63岁的荷兰籍男性,HIV血清学阴性,出现了持续6个月的肛门疼痛和瘙痒、肛周溃疡及单个结肠溃疡。怀疑为克罗恩病;该患者接受了皮质类固醇治疗,但后来死亡。尸检显示为播散性组织胞浆菌病,这是一种在荷兰罕见的真菌病。该患者曾去过洪都拉斯。本病例报告表明,播散性组织胞浆菌病可能会酷似克罗恩病,从而导致诊断延误。

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引用本文的文献

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AIDS-related disseminated histoplasmosis in San Francisco, California.加利福尼亚州旧金山市与艾滋病相关的播散性组织胞浆菌病。
West J Med. 1997 Nov;167(5):315-21.