Uhlenbruck G, Reese I, Vaith P, Haupt H
J Clin Chem Clin Biochem. 1979 Jan;17(1):29-34. doi: 10.1515/cclm.1979.17.1.29.
Human serum glycoproteins can be classified into those containing N-acetyl-D-galactosamine and into those lacking this hexosamine. The N-acetyl-D-galactosamine-containing serum glycoproteins have alkali-labile chains containing this hexosamine linked O-glycosidically to hydroxy amino acids. These alkali-labile chains can be demonstrated in neuraminic acid free serum glycoproteins by gas liquid chromatography and by using precipitating lectins from invertebrates and plants. They are represented by two chains, one containing only N-acetyl-D-galactosamine, the other with D-galactose linked (1--3) beta-glycosidically to this hexosamine forming a disaccharide. Serologically these two chains, which usually occur together on one molecule, can be characterized by their reaction with lectins from Helix pomatia (anti-A like) and from Agaricus bisporus and Arachis hypogaea (anti-TF specificity).
人血清糖蛋白可分为含N-乙酰-D-半乳糖胺的糖蛋白和不含这种己糖胺的糖蛋白。含N-乙酰-D-半乳糖胺的血清糖蛋白具有碱不稳定链，该链含有通过O-糖苷键与羟基氨基酸相连的这种己糖胺。通过气相色谱法以及使用来自无脊椎动物和植物的沉淀凝集素，可在无神经氨酸的血清糖蛋白中证实这些碱不稳定链。它们由两条链代表，一条链仅含N-乙酰-D-半乳糖胺，另一条链中D-半乳糖通过β-糖苷键（1→3）与该己糖胺相连形成二糖。从血清学角度来看，这两条通常存在于一个分子上的链，可通过它们与来自苹果螺（抗A样）、双孢蘑菇和落花生（抗TF特异性）的凝集素的反应来表征。
