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Serological studies on the carbohydrate moiety of human tyrosinase.

作者信息

Herrmann W P, Uhlenbruck G

出版信息

Arch Dermatol Res (1975). 1975 Dec 31;254(3):275-80. doi: 10.1007/BF00557969.

DOI:10.1007/BF00557969
PMID:813583
Abstract
  1. Human tyrosinase is a glycoprotein containing N-acetylneuraminic acid. 2. The terminal neuraminic acid groups are linked to D-galactose. 3. In addition, human tyrosinase reacts strongly with concanavalin A. This finding indicates that the carbohydrate chain of human tyrosinase contains D-mannose. 4. The data presented here suggest that the carbohydrate moiety of human tyrosinase is linked to the protein core in an alkali-stable form. 5. Alkali-labile carbohydrate chains which occur predominantly in membrane bound glycoproteins could not be demonstrated serologically.
摘要

相似文献

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引用本文的文献

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An animal model for the survival of tyrosinase isozymes in serum.
Arch Dermatol Res. 1984;276(2):111-4. doi: 10.1007/BF00511067.
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Demonstration of carbohydrates in premelanosomes by ultrastructural cytochemistry.通过超微结构细胞化学对前黑素小体中的碳水化合物进行显示。
Arch Dermatol Res. 1985;278(2):148-52. doi: 10.1007/BF00409222.
3
Enzyme histochemistry of human melanomas and pigmented naevi with special reference to alpha-D-mannosidase activity.人类黑色素瘤和色素痣的酶组织化学，特别提及α-D-甘露糖苷酶活性

本文引用的文献

1
[Immunologic analysis of tyrosinase in malignant melanoma, nevi and clinically normal skin].[恶性黑色素瘤、痣及临床正常皮肤中酪氨酸酶的免疫学分析]
Arch Dermatol Forsch. 1971;241(1):65-74.
2
Blood group substance A prepared from human seminal plasma.
Arch Dermatol Forsch. 1973 Jan 29;246(1):47-54. doi: 10.1007/BF00595486.
3
Immunoelectrophoretic studies on glycoproteins of the human seminal plasma.人精浆糖蛋白的免疫电泳研究。
Arch Dermatol Forsch. 1972;243(4):341-5. doi: 10.1007/BF00620415.
Histochem J. 1986 Sep;18(9):472-80. doi: 10.1007/BF01675614.
4
Cloning and expression of cDNA encoding mouse tyrosinase.编码小鼠酪氨酸酶的cDNA的克隆与表达
Nucleic Acids Res. 1986 Mar 25;14(6):2413-27. doi: 10.1093/nar/14.6.2413.
4
The biochemistry of plant lectins (phytohemagglutinins).植物凝集素（植物血凝素）的生物化学
Annu Rev Biochem. 1973;42(0):541-74. doi: 10.1146/annurev.bi.42.070173.002545.
5
Further characterization of some heterophile agglutinins reacting with alkali-labile carbohydrate chains of human erythrocyte glycoproteins.一些与人类红细胞糖蛋白的碱不稳定碳水化合物链发生反应的嗜异性凝集素的进一步特性研究。
Vox Sang. 1975;28(2):133-48. doi: 10.1111/j.1423-0410.1975.tb02751.x.
6
Tyrosinase as glycoprotein.作为糖蛋白的酪氨酸酶。
Arch Dermatol Forsch. 1975;252(3):211-6. doi: 10.1007/BF00557921.