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坎塔布里亚首发精神分裂症研究:总体研究结果总结

The Cantabria first episode schizophrenia study: a summary of general findings.

作者信息

Vázquez-Barquero J L, Cuesta Nuñez M J, de la Varga M, Herrera Castanedo S, Gaite L, Arenal A

机构信息

Social Psychiatry Research Unit of Cantabria, University Hospital Marqués de Valdecilla, Cantabria University, Santander, Spain.

出版信息

Acta Psychiatr Scand. 1995 Mar;91(3):156-62. doi: 10.1111/j.1600-0447.1995.tb09759.x.

DOI:10.1111/j.1600-0447.1995.tb09759.x
PMID:7625188
Abstract

This article describes the general findings of the initial cross-sectional stage of a prospective follow-up study of all first episodes of schizophrenia that occurred in the Autonomous Community of Cantabria over a 2-year period and that established contact with any mental health service. The project comprises: i) a 2-year cross-sectional stage, in which the sample was gathered and studied with structured psychiatric instruments such as the Present State Examination and the Scales for the Assessment of Negative and Positive Symptoms (SANS and SAPS), and; ii) a continuous follow-up. We detected, in the risk age ranged of 15-54 years, an incidence of 1.9 per 10,000 inhabitants per year for schizophrenia and of 1.3 per 10,000 inhabitants per year for the S+ CATEGO diagnosis, without any significant gender difference of morbidity. The mean age for the total schizophrenic population was 26 years, being significantly higher in women than in men. In contrast with what happens with marital status, type of household or urban/rural way of life, there was no gender difference in relation to the other sociodemographic variables. The way in which nosological and clinical variables are associated with first episodes of schizophrenia was also examined in this study. We found that 75% of patients reached a maximum CATEGO-ID level, 71% received a S+ CATEGO diagnosis, 59% presented first-rank symptoms of schizophrenia and that the percentage of a schizophrenic negative syndrome, as identified by the SANS and SAPS, was very low.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

本文描述了一项前瞻性随访研究初始横断面阶段的总体研究结果。该研究针对坎塔布里亚自治区在两年内发生的所有精神分裂症首发病例,且这些病例与任何心理健康服务机构建立了联系。该项目包括:i)一个为期两年的横断面阶段,在此阶段通过结构化精神病学工具(如《现状检查》和《阴性与阳性症状评定量表》(SANS和SAPS))收集样本并进行研究;ii)持续随访。我们发现,在15至54岁的风险年龄范围内,精神分裂症的发病率为每年每10000名居民中有1.9例,S + CATEGO诊断的发病率为每年每10000名居民中有1.3例,发病率无显著性别差异。精神分裂症患者的平均年龄为26岁,女性明显高于男性。与婚姻状况、家庭类型或城乡生活方式不同,在其他社会人口统计学变量方面没有性别差异。本研究还考察了疾病分类学和临床变量与精神分裂症首发的关联方式。我们发现,75%的患者达到了最高CATEGO - ID水平,71%的患者得到了S + CATEGO诊断,59%的患者出现了精神分裂症的一级症状,并且根据SANS和SAPS确定的精神分裂症阴性综合征的比例非常低。(摘要截选至250字)

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