Vázquez-Barquero J L, Cuesta Nuñez M J, Herrera Castanedo S, Diez Manrique J F, Pardo G, Dunn G
Clinical and Social Psychiatry Research Unit, University Hospital Marqués de Valdecilla, Cantabria University, Santander, Spain.
Acta Psychiatr Scand. 1996 Sep;94(3):149-55. doi: 10.1111/j.1600-0447.1996.tb09840.x.
This paper examines the association of clinical and sociodemographic factors, including age and sex, with the diagnostic characteristics of first episodes of schizophrenia. The study included all patients with a first episode of schizophrenia who made contact with any of the public mental health services of the Autonomous Region of Cantabria in Northern Spain over a period of 2 years. Diagnostic characteristics were determined using the Spanish version of the Present State Examination (PSE-9), and the Scales for the Assessment of Positive and Negative Symptoms (SAPS and SANS, respectively). The study confirms that the onset of schizophrenia tends to occur earlier in men than in women. However, neither sex nor age of onset were found to be associated with the clinical and psychopathological characteristics of the patients as established by the PSE-CATEGO-ID system. Furthermore, no other factors were found to be associated with these diagnostic characteristics. Being female, having a family history of mental illness, and a poor premorbid adjustment were found to predict negative symptoms as defined by SANS/SAPS scales.
本文研究了包括年龄和性别在内的临床及社会人口学因素与精神分裂症首次发作的诊断特征之间的关联。该研究纳入了在两年时间内与西班牙北部坎塔布里亚自治区任何公共心理健康服务机构有接触的所有精神分裂症首次发作患者。使用西班牙语版的《现状检查》（PSE - 9）以及阳性与阴性症状评定量表（分别为SAPS和SANS）来确定诊断特征。研究证实，精神分裂症的发病往往男性比女性更早。然而，未发现发病的性别和年龄与PSE - CATEGO - ID系统所确定的患者临床及精神病理学特征相关。此外，未发现其他因素与这些诊断特征相关。研究发现，女性、有精神疾病家族史以及病前适应不良可预测SANS/SAPS量表所定义的阴性症状。
