Hira S K, Spruyt A B, Feldblum P J, Sunkutu M R, Glover L H, Steiner M J
Dermato-Venereology Clinic, University Teaching Hospital, Lusaka, Zambia.
Am J Public Health. 1995 Aug;85(8 Pt 1):1098-103. doi: 10.2105/ajph.85.8_pt_1.1098.
This study assessed the acceptability of three nonoxynol-9 spermicides among persons attending a sexually transmitted disease clinic in Lusaka, Zambia.
Spermicidal foam, suppositories, and foaming tablets were evaluated. Women (n = 114) and men (n = 150) attending an sexually transmitted disease clinic were enrolled. After each participant used two products, each for 2 weeks, consistency of use and acceptability were evaluated.
At admission, most women (74%) and men (58%) were not using any family planning method. Moreover, most women (85%) and men (98%) had at least one sexually transmitted disease or genital infection. During the study, the proportion of coital episodes protected by spermicide use was high, yet loss to follow-up and discontinuation were also substantial. Discontinuation was frequently unrelated to acceptability. Women and men rated all three products positively along several acceptability parameters. Foam was the least desirable delivery system due to excess messiness.
The results of this study suggest that it is feasible to distribute spermicides to women and men at increased risk for sexually transmitted disease and that the products will be used. Further research should be done among different populations and include other spermicidal delivery mechanisms.
本研究评估了三种壬苯醇醚 - 9杀精剂在赞比亚卢萨卡一家性传播疾病诊所就诊人群中的可接受性。
对杀精泡沫、栓剂和发泡片进行了评估。招募了在一家性传播疾病诊所就诊的女性(n = 114)和男性(n = 150)。在每位参与者使用两种产品,每种使用2周后,评估使用的一致性和可接受性。
入院时,大多数女性(74%)和男性(58%)未使用任何计划生育方法。此外,大多数女性(85%)和男性(98%)至少患有一种性传播疾病或生殖器感染。在研究期间,使用杀精剂保护的性交次数比例较高,但失访和停药情况也很严重。停药情况通常与可接受性无关。女性和男性在几个可接受性参数方面对所有三种产品的评价都很高。由于过于 messy,泡沫是最不理想的给药系统。
本研究结果表明,向性传播疾病风险增加的女性和男性分发杀精剂是可行的,并且这些产品将会被使用。应在不同人群中开展进一步研究,并纳入其他杀精剂给药机制。