Neuzil K M, Gruber W C, Chytil F, Stahlman M T, Graham B S
Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.
Antimicrob Agents Chemother. 1995 May;39(5):1191-3. doi: 10.1128/AAC.39.5.1191.
Infants with respiratory syncytial virus infection have low serum vitamin A levels. We treated 21 respiratory syncytial virus-infected children with 12,500 to 25,000 IU of oral vitamin A. Vitamin A levels were normalized at 6 h, and none of the children experienced vitamin A toxicity or exacerbation of respiratory illness. Vitamin A treatment of previously healthy respiratory syncytial virus-infected infants at these doses is safe and well tolerated.
感染呼吸道合胞病毒的婴儿血清维生素A水平较低。我们对21名感染呼吸道合胞病毒的儿童给予12,500至25,000国际单位的口服维生素A进行治疗。维生素A水平在6小时时恢复正常,且没有儿童出现维生素A中毒或呼吸道疾病加重的情况。以这些剂量对先前健康的感染呼吸道合胞病毒的婴儿进行维生素A治疗是安全的,且耐受性良好。