巴塘紫菀中的药用酸皂苷。

Medicagenic acid saponins from Aster batangensis.

作者信息

Shao Y, Zhou B, Ma K, Wu H, Lin L, Cordell G A

机构信息

Shanghai Institute of Materia Medica, Academia Sinica, P.R. China.

出版信息

Phytochemistry. 1995 Jul;39(4):875-81. doi: 10.1016/0031-9422(95)00016-z.

DOI:10.1016/0031-9422(95)00016-z

PMID:7626267

Abstract

Two new medicagenic acid saponins, named asterbatanoside J and K, were isolated from the roots of Aster batangensis. On the basis of chemical and spectral studies especially 2D NMR including COSY, HETCOR, HMQC, HOHAHA, TOCSY, ROESY and HMBC techniques, their structures were established as 3-O-beta-D-glucopyranosyl-(1--> 6)-beta-D-glucopyranosyl-2 beta, 3 beta-dihydroxy-olean-12-en-23 alpha, 28-dioic acid- 28-O-alpha-L-arabinopyranosyl-(1-->3)-alpha-L- rhamnopyranosyl-(1-->2)-beta-D-fucopyranoside and 3-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl- medicagenic acid-28-O-beta-D-xylopyranosyl-(-->4)-[alpha-L- arabinopyranosyl-(1 -->3)-alpha-L-rhamnopyranosyl-(1-->2) -beta-D-fucopyranside, respectively.

摘要

从巴塘紫菀（Aster batangensis）根部分离得到两种新的药用酸皂苷，命名为紫菀巴塘苷J和K。基于化学和光谱研究，特别是二维核磁共振（2D NMR），包括COSY、HETCOR、HMQC、HOHAHA、TOCSY、ROESY和HMBC技术，确定它们的结构分别为3-O-β-D-吡喃葡萄糖基-(1→6)-β-D-吡喃葡萄糖基-2β,3β-二羟基-齐墩果-12-烯-23α,28-二酸-28-O-α-L-吡喃阿拉伯糖基-(1→3)-α-L-吡喃鼠李糖基-(1→2)-β-D-吡喃岩藻糖苷和3-O-β-D-吡喃葡萄糖基-(1→6)-β-D-吡喃葡萄糖基-药用酸-28-O-β-D-吡喃木糖基-(→4)-[α-L-吡喃阿拉伯糖基-(1→3)-α-L-吡喃鼠李糖基-(1→2)-β-D-吡喃岩藻糖苷。