朱砂根中的三萜皂苷。

Triterpenoid saponins from Ardisia crenata.

作者信息

Jia Z, Koike K, Ohmoto T, Ni M

机构信息

Department of Pharmacognosy, School of Pharmaceutical Sciences, Toho University, Chiba, Japan.

出版信息

Phytochemistry. 1994 Nov;37(5):1389-96. doi: 10.1016/s0031-9422(00)90418-7.

DOI:10.1016/s0031-9422(00)90418-7

PMID:7765756

Abstract

Two novel triterpenoid saponins, ardisicrenoside A [3 beta-O-(alpha-L-rhamnopyranosyl-(1-->2)-[beta-D-glucopyranosyl- (1-->4)-[beta-D-glucopyranosyl-(1-->2)]-alpha-L-arabinopyranosyl)- 13 beta,28-epoxy-16 alpha,30-oleananediol] and ardisicrenoside B [3 beta-O-(beta-D-xylopyranosyl-(1-->2)-[beta-D- glucopyranosyl-(1-->4)-[beta-D-glucopyranosyl-(1-->2)]- alpha-L-arabinopyranosyl)-13 beta,28-epoxy-16 alpha,30-oleananediol] were isolated from the roots of Ardisia crenata. Two known triterpenoid saponins, ardisiacrispins A and B were also isolated from this source. Their structures were determined mainly by 2D NMR (COSY, HOHAHA, HETCOR, HMBC and ROESY) experiments. The aglycones are the new 13 beta,28-epoxy-3 beta,16 alpha,30-oleananetriol for ardisicrenosides A and B.

摘要

从朱砂根的根部分离得到了两种新型三萜皂苷，分别为朱砂根皂苷A [3β - O - (α - L - 鼠李糖基 - (1→2) - [β - D - 葡萄糖基 - (1→4) - [β - D - 葡萄糖基 - (1→2)] - α - L - 阿拉伯糖基) - 13β,28 - 环氧 - 16α,30 - 齐墩果烷二醇] 和朱砂根皂苷B [3β - O - (β - D - 木糖基 - (1→2) - [β - D - 葡萄糖基 - (1→4) - [β - D - 葡萄糖基 - (1→2)] - α - L - 阿拉伯糖基) - 13β,28 - 环氧 - 16α,30 - 齐墩果烷二醇]。还从该来源分离得到了两种已知的三萜皂苷，即朱砂根皂苷A和B。它们的结构主要通过二维核磁共振（COSY、HOHAHA、HETCOR、HMBC和ROESY）实验确定。对于朱砂根皂苷A和B，其苷元是新的13β,28 - 环氧 - 3β,16α,30 - 齐墩果烷三醇。