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类风湿性关节炎患者白内障摘除及人工晶状体植入术后的炎症反应

Inflammation after cataract extraction and intraocular lens implantation in patients with rheumatoid arthritis.

作者信息

Matsuo T, Fujiwara M, Matsuo N

机构信息

Department of Ophthalmology, Okayama University Medical School, Japan.

出版信息

Br J Ophthalmol. 1995 Jun;79(6):549-53. doi: 10.1136/bjo.79.6.549.

Abstract

AIMS

The purpose of this study was to examine whether preoperative activity of rheumatoid arthritis influences the extent of anterior chamber inflammation after cataract extraction and intraocular lens implantation.

METHODS

The medical records of 23 consecutive patients (33 eyes) with rheumatoid arthritis, who underwent cataract extraction with intraocular lens implantation, were reviewed during a 4 year period from April 1990 to March 1994.

RESULTS

Eleven patients who still showed a 1+ level of aqueous cells 1 month after the surgery had significantly higher titres of rheumatoid factor preoperatively, compared with the other 12 patients who showed no aqueous cells (p = 0.0019, Mann-Whitney U test). The persistence of aqueous cells also had a significant correlation with extracapsular cataract extraction compared with phacoemulsification (p = 0.0391, chi 2 test). Multivariate analysis showed that the titre of rheumatoid factor was the more significant element to determine the persistent aqueous inflammation. All the eyes, except for four which had a macular hole, optic disc atrophy, or retinitis pigmentosa gained visual acuity of 20/30 or better. The aqueous cells cleared 3 months after the surgery and left no complications in any of the eyes.

CONCLUSION

Intraocular lens implantation is basically a safe procedure for patients with rheumatoid arthritis, although postoperative aqueous inflammation tends to be persistent in patients with high titres of rheumatoid factor.

摘要

目的

本研究旨在探讨类风湿关节炎患者术前的活动情况是否会影响白内障摘除及人工晶状体植入术后前房炎症的程度。

方法

回顾1990年4月至1994年3月这4年间连续23例(33只眼)接受白内障摘除及人工晶状体植入术的类风湿关节炎患者的病历。

结果

术后1个月仍有1+级房水细胞的11例患者术前类风湿因子滴度显著高于另外12例无房水细胞的患者(曼-惠特尼U检验,p = 0.0019)。与超声乳化白内障吸除术相比,囊外白内障摘除术后房水细胞持续存在也有显著相关性(卡方检验,p = 0.0391)。多因素分析表明,类风湿因子滴度是决定房水炎症持续存在的更重要因素。除4只眼有黄斑裂孔、视盘萎缩或视网膜色素变性外,所有患眼视力均达到或优于20/30。术后3个月房水细胞消失,所有患眼均无并发症。

结论

对于类风湿关节炎患者,人工晶状体植入术基本上是一种安全的手术,尽管类风湿因子滴度高的患者术后房水炎症往往会持续存在。

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Rheumatic iritis and iridocyclitis.风湿性虹膜炎和虹膜睫状体炎。
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Signs and symptoms of uveitis. I. Anterior uveitis.葡萄膜炎的体征和症状。I. 前葡萄膜炎。
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Retinal vasculitis in rheumatoid arthritis.类风湿关节炎中的视网膜血管炎。
Br Med J (Clin Res Ed). 1981 May 30;282(6278):1745-6. doi: 10.1136/bmj.282.6278.1745.

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