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[2型糖尿病中的大血管病变。拉瓦尔南部研究]

[Macroangiopathy in type II diabetes. The Raval South study].

作者信息

Mur Martí T, Franch Nadal J, Morato Griera J, Mena González A, Vilarrubias Calaf M, Llobera Serentill A

机构信息

Area Básica de Salud Raval Sud, Barcelona.

出版信息

Aten Primaria. 1995 Jun 30;16(2):67-72.

PMID:7626734
Abstract

OBJECTIVE

To study the prevalence of clinical forms of diabetic macroangiopathy (DM) and its risk factors.

DESIGN

A descriptive crossover study.

SETTING

An elderly and socio-economically very depressed population in Raval Sud Health District (HD), Barcelona.

PATIENTS AND OTHER PARTICIPANTS

Random sampling of type II diabetes patients (n = 387) registered in the HD (6.6% prevalence).

MEASUREMENTS AND MAIN RESULTS

Each patient was examined for the presence of diagnostic criteria of peripheric, cerebral or coronary vasculopathy (VP); as well as for the possible risk factors (age, gender, years of the DM's evolution, tobacco, hypertension, obesity, glycosilated haemoglobin and dyslipemia). Prevalences obtained were: peripheric VP = 24.5%, cerebral VP = 9.5%, coronary VP = 18.1%. 30.5% of the diabetics had some form of macroangiopathy. The main risk factors for all the clinical forms (p < 0.001) were age and the length of evolution of DM, tobacco mainly for peripheric VP (p < 0.001), systolic Hypertension for cerebral VP (p = 0.03) and Hypertriglyceridaemia for peripheric VP (p < 0.01).

CONCLUSIONS

Macroangiopathy affects a high percentage (30.5%) of type 2 diabetics. The principal risk factors are those associated with tobacco, hypertension and hypertriglyceridaemia, all of which we can affect and control.

摘要

目的

研究糖尿病大血管病变(DM)的临床类型患病率及其危险因素。

设计

一项描述性交叉研究。

地点

巴塞罗那拉瓦尔南区卫生区(HD)一个老年且社会经济状况非常低迷的人群。

患者及其他参与者

对HD登记的II型糖尿病患者进行随机抽样(n = 387)(患病率6.6%)。

测量与主要结果

检查每位患者是否存在外周、脑或冠状动脉血管病变(VP)的诊断标准;以及可能的危险因素(年龄、性别、糖尿病病程、吸烟、高血压、肥胖、糖化血红蛋白和血脂异常)。获得的患病率为:外周VP = 24.5%,脑VP = 9.5%,冠状动脉VP = 18.1%。30.5%的糖尿病患者有某种形式的大血管病变。所有临床类型的主要危险因素(p < 0.001)是年龄和糖尿病病程,吸烟主要与外周VP相关(p < 0.001),收缩期高血压与脑VP相关(p = 0.03),高甘油三酯血症与外周VP相关(p < 0.01)。

结论

大血管病变影响高比例(30.5%)的2型糖尿病患者。主要危险因素是与吸烟、高血压和高甘油三酯血症相关的因素,所有这些我们都可以影响和控制。

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