The tropomodulin (Tmod) gene maps to chromosome 4, closely linked to Mup1.

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作者信息

White R A, Dowler L L, Woo M, Adkison L R, Pal S, Gershon D, Fowler V M

机构信息

Section of Genetics, Children's Mercy Hospital, Kansas City, Missouri 64108, USA.

出版信息

Mamm Genome. 1995 May;6(5):332-3. doi: 10.1007/BF00364795.

DOI:10.1007/BF00364795

PMID:7626883

Abstract

摘要

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The tropomodulin (Tmod) gene maps to chromosome 4, closely linked to Mup1.

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引用本文的文献

Tropomodulins: pointed-end capping proteins that regulate actin filament architecture in diverse cell types.原肌球蛋白：顶端封闭蛋白，调控多种细胞类型中肌动蛋白丝的结构。

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The junctional complex of the membrane skeleton.膜骨架的连接复合体。

Semin Hematol. 1993 Jan;30(1):74-83.

Tropomodulin is associated with the free (pointed) ends of the thin filaments in rat skeletal muscle.原肌球蛋白与大鼠骨骼肌细肌丝的游离（尖）端相关联。

J Cell Biol. 1993 Jan;120(2):411-20. doi: 10.1083/jcb.120.2.411.

Isoform-specific interaction of tropomodulin with skeletal muscle and erythrocyte tropomyosins.原肌球蛋白调节蛋白与骨骼肌及红细胞原肌球蛋白的同工型特异性相互作用。

J Biol Chem. 1994 Nov 4;269(44):27510-8.

Tropomodulin caps the pointed ends of actin filaments.原肌球蛋白封闭肌动蛋白丝的尖端。

J Cell Biol. 1994 Dec;127(6 Pt 1):1627-35. doi: 10.1083/jcb.127.6.1627.

Confidence limits for estimates of gene linkage based on analysis of recombinant inbred strains.基于重组近交系分析的基因连锁估计的置信限

J Hered. 1985 Nov-Dec;76(6):436-40. doi: 10.1093/oxfordjournals.jhered.a110140.

Identification and purification of a novel Mr 43,000 tropomyosin-binding protein from human erythrocyte membranes.

J Biol Chem. 1987 Sep 15;262(26):12792-800.

Tropomodulin: a cytoskeletal protein that binds to the end of erythrocyte tropomyosin and inhibits tropomyosin binding to actin.原肌球蛋白调节蛋白：一种细胞骨架蛋白，可与红细胞原肌球蛋白的末端结合，并抑制原肌球蛋白与肌动蛋白的结合。

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Molecular cloning and characterization of human fetal liver tropomodulin. A tropomyosin-binding protein.人胎儿肝脏原肌球蛋白调节蛋白的分子克隆与特性分析。一种原肌球蛋白结合蛋白。

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