Lustig J P, Lugassy G, Neder A, Sigler E
Department of Oral and Maxillofacial Surgery, Barzilai Medical Center, Ashkelon, Israel.
Eur J Cancer B Oral Oncol. 1995 Jan;31B(1):68-72. doi: 10.1016/0964-1955(94)00044-5.
Fanconi's anaemia (FA) is a rare autosomal recessive syndrome characterised by progressive lethal pancytopenia, skeletal abnormalities, hyperpigmentation and increased chromosomal aberrations. A high incidence of leukaemia and hepatocellular and squamous cell carcinomas (SCC) have been reported in FA patients. A rare case of SCC of the dorsum of the tongue in a FA patient is presented. A review of the reported cases of head and neck carcinoma in FA patients shows a different male:female ratio than previously reported, and a high incidence of carcinoma of the tongue.
范科尼贫血（FA）是一种罕见的常染色体隐性综合征，其特征为进行性致死性全血细胞减少、骨骼异常、色素沉着过度和染色体畸变增加。据报道，FA患者患白血病、肝细胞癌和鳞状细胞癌（SCC）的发生率很高。本文报告了1例FA患者舌背SCC的罕见病例。对已报道的FA患者头颈部癌病例的回顾显示，其男女比例与先前报道的不同，且舌癌发生率很高。
