Williams K, Morton P G
AACN Clin Issues. 1995 Aug;6(3):375-86; quiz 491-2. doi: 10.1097/00044067-199508000-00003.
Rapid diagnosis and treatment of myocardial infarction are essential for maximizing patient survival. Recent advances in early detection of creatine kinase myocardial band isoforms and other chemical markers, as well as increased use of echocardiography, magnetic resonance imaging, and nuclear imaging, have enhanced the diagnostic capabilities for providers caring for a patient suspected of myocardial infarction. In management of myocardial infarction, the focus continues to be primarily on using thrombolytics, percutaneous transluminal coronary angioplasty, and coronary bypass surgery. In addition, an array of pharmacologic agents aimed at reducing cardiac muscle damage, alleviating reperfusion injuries, and preventing thrombus formation are undergoing clinical trials. These agents may hold promise for the future treatment of myocardial infarction.
心肌梗死的快速诊断和治疗对于最大限度提高患者生存率至关重要。肌酸激酶心肌带同工型及其他化学标志物早期检测方面的最新进展,以及超声心动图、磁共振成像和核成像使用的增加,增强了为疑似心肌梗死患者提供护理的医疗人员的诊断能力。在心肌梗死的治疗中,重点仍然主要是使用溶栓剂、经皮冠状动脉腔内血管成形术和冠状动脉搭桥手术。此外,一系列旨在减少心肌损伤、减轻再灌注损伤和预防血栓形成的药物正在进行临床试验。这些药物可能为未来心肌梗死的治疗带来希望。