Smith C, Farr G, Feldblum P J, Spence A
Parkside Health Trust, Raymede Health Centre, London, United Kingdom.
Contraception. 1995 May;51(5):289-91. doi: 10.1016/0010-7824(95)00075-l.
Standard instructions for diaphragm use call for an individually sized latex diaphragm, used in conjunction with spermicide jelly. However, some investigators have reported that the diaphragm can be effective without a spermicide. A non-randomized trial designed to measure the contraceptive effectiveness of the diaphragm used without spermicide was conducted. A total of 110 self-selected women were enrolled to use a non-spermicide fit-free (60mm) diaphragm for a period of one year. They were advised to wear the diaphragm continuously, removing it once each day for washing but not within six hours after intercourse. Product-related problems related to insertion, retention and removal were few at both the 6- and 12-month follow-up visits, most commonly odor. The 12-month life table accidental pregnancy rate during typical use was 24.1 per 100 women (29.5 per 100 women without female barrier experience and 17.9 per 100 women with barrier experience). Over 85% of the women who returned for follow-up visits reported using the diaphragm during every act of intercourse. Until better data refute the traditional recommendations, users should be advised to add spermicide to fitted latex diaphragms.
使用隔膜的标准说明要求使用个体尺寸合适的乳胶隔膜，并与杀精剂凝胶一起使用。然而，一些研究人员报告称，不使用杀精剂时隔膜也可能有效。开展了一项非随机试验，旨在测量不使用杀精剂时隔膜的避孕效果。共有110名自行选择的女性参与，使用无杀精剂、尺寸通用（60毫米）的隔膜，为期一年。建议她们持续佩戴隔膜，每天取出一次进行清洗，但性交后6小时内不要取出。在6个月和12个月的随访中，与插入、留存和取出相关的产品问题较少，最常见的是异味。典型使用期间12个月的生命表意外妊娠率为每100名女性24.1例（无女性屏障避孕经验的女性每100名中有29.5例，有屏障避孕经验的女性每100名中有17.9例）。超过85%前来随访的女性报告在每次性交时都使用隔膜。在有更好的数据反驳传统建议之前，应建议使用者在合适的乳胶隔膜中添加杀精剂。
