[Arguments for early treatment of refractory schizophrenia].

The authors, taking up their experience and the literature, attempt to view the precociousness of alternative, classical neuroleptic treatments in schizophrenia, from notion of treatment-resistant schizophrenia, precocious refractory and intolerance. Until now, clozapine was administrated to patients lasting resistant and in mainly cases hospitalized since many years. As such as quality of life and economy of health, it would be desirable to quickly think of alternatives neuroleptic's therapeutic protocols and clozapine in the treatment-resistant schizophrenias or those presenting an intolerance.