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活性氧作为第二信使在矮牵牛细胞中诱导交替氧化酶基因表达中的作用。

A role for active oxygen species as second messengers in the induction of alternative oxidase gene expression in Petunia hybrida cells.

作者信息

Wagner A M

机构信息

Department of Physiology and Biochemistry of Plants, Vrije Universiteit, Amsterdam, The Netherlands.

出版信息

FEBS Lett. 1995 Jul 17;368(2):339-42. doi: 10.1016/0014-5793(95)00688-6.

DOI:10.1016/0014-5793(95)00688-6
PMID:7628633
Abstract

Incubation of Petunia hybrida cells with H2O2 leads to an increase in alternative oxidase activity measured after 24 h. This increased activity is accompanied by an increase in alternative oxidase protein. A model is presented for the regulation of alternative oxidase protein synthesis in which active oxygen species and especially H2O2 play a crucial role as second messengers in the signal transducing pathway from the mitochondria to the nucleus. It is proposed that also the induction of the alternative oxidase by salicylic acid is mediated via H2O2.

摘要

用H₂O₂处理矮牵牛细胞24小时后,交替氧化酶活性增加。这种活性增加伴随着交替氧化酶蛋白的增加。本文提出了一个交替氧化酶蛋白合成调控模型,其中活性氧物质尤其是H₂O₂作为线粒体到细胞核信号转导途径中的第二信使发挥关键作用。有人提出水杨酸对交替氧化酶的诱导也是通过H₂O₂介导的。

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