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运动中的氧化应激:抗氧化营养素的影响

Oxidative stress during exercise: implication of antioxidant nutrients.

作者信息

Ji L L

机构信息

Department of Kinesiology and Interdepartmental Program of Nutritional Sciences, University of Wisconsin-Madison, USA.

出版信息

Free Radic Biol Med. 1995 Jun;18(6):1079-86. doi: 10.1016/0891-5849(94)00212-3.

DOI:10.1016/0891-5849(94)00212-3
PMID:7628730
Abstract

Research evidence has accumulated in the past decade that strenuous aerobic exercise is associated with oxidative stress and tissue damage in the body. There is indication that generation of oxygen free radicals and other reactive oxygen species may be the underlying mechanism for exercise-induced oxidative damage, but a causal relationship remains to be established. Enzymatic and nonenzymatic antioxidants play a vital role in protecting tissues from excessive oxidative damage during exercise. Depletion of each of the antioxidant systems increases the vulnerability of various tissues and cellular components to reactive oxygen species. Because acute strenuous exercise and chronic exercise training increase the consumption of various antioxidants, it is conceivable that dietary supplementation of specific antioxidants would be beneficial.

摘要

在过去十年中,已有研究证据表明,剧烈有氧运动与体内的氧化应激和组织损伤有关。有迹象表明,氧自由基和其他活性氧的产生可能是运动诱导氧化损伤的潜在机制,但因果关系仍有待确定。酶促抗氧化剂和非酶促抗氧化剂在运动期间保护组织免受过度氧化损伤方面起着至关重要的作用。每种抗氧化系统的消耗都会增加各种组织和细胞成分对活性氧的易感性。由于急性剧烈运动和慢性运动训练会增加各种抗氧化剂的消耗,可以想象,膳食补充特定的抗氧化剂会有益处。

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