Puavilai S, Sakuntabhai A, Sriprachaya-Anunt S, Rajatanavin N, Charuwichitratana S
Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
J Med Assoc Thai. 1995 Feb;78(2):72-5.
One hundred patients with biopsy-proven erythema nodosum were studied at Ramathibodi Hospital from 1982 to 1992 to find out the etiology of this disease. Eighty-eight were females while twelve were males, with an age range from 6 to 72 years old (mean, 31 years old). Abnormal laboratory findings in these patients included elevation of erythrocyte sedimentation rate (76.9%), increase anti-streptolysin-O titer (10.7%), abnormal chest roentgenogram (16.7%), positive tuberculin test (50%). The cause of erythema nodosum is still unknown in a large group of patients, and it was found only in twenty-eight patients (28%). Twelve patients had tuberculosis, seven had history of antibiotic administration, six probably had streptococcal infection and the other three had Behcet's disease.
1982年至1992年期间，拉玛提波迪医院对100例经活检证实为结节性红斑的患者进行了研究，以查明该病的病因。其中88例为女性，12例为男性，年龄范围为6至72岁（平均31岁）。这些患者的实验室检查异常包括红细胞沉降率升高（76.9%）、抗链球菌溶血素O滴度升高（10.7%）、胸部X线片异常（16.7%）、结核菌素试验阳性（50%）。在一大组患者中，结节性红斑的病因仍然不明，仅在28例患者（28%）中发现了病因。12例患者患有结核病，7例有抗生素用药史，6例可能有链球菌感染，另外3例患有白塞病。
