Joffe M, Villard L, Li Z, Plowman R, Vessey M
Academic Department of Public Health, St Mary's Hospital Medical School, London.
J Epidemiol Community Health. 1995 Jun;49(3):314-9. doi: 10.1136/jech.49.3.314.
To establish the degree of validity of data on time to pregnancy, derived retrospectively using a short questionnaire.
Information from the questionnaire was compared with data that had been collected concurrently from the same individuals.
Questionnaires were mailed to 1647 women who continue to be followed up by the Oxford Family Planning Association contraceptive study, and a further 424 were approached for personal interview. Response rates were 91% and 79% respectively.
Matching was successful in 91% of pregnancies. Median recall time was 14 years (interquartile range, 11-16 years). At the group level, remarkably good agreement was found between the two sources of information, presented as cumulative percentage distributions of live births. The findings were at least as good with longer recall (> 14 years) as with shorter recall. Digit performance was present to a limited degree. At the individual level, some misclassification was evident, which has implications for statistical power. For detection of clinical infertility (no conception within 12 months), the sensitivity was in the range 67%-91%, and the specificity was 92%-96%. Variations with format, duration of recall, age at delivery, year of birth, parity, social class, smoking habit, last contraceptive method, and outcome (live birth or not) were generally small, and were not statistically significant.
Time to pregnancy is a sensitive way of assessing reproductive function in either sex. Valid data at a group level can be derived retrospectively, with a long duration of recall, using a short questionnaire.
通过一份简短问卷回顾性地确定受孕时间数据的有效程度。
将问卷信息与从同一人群中同时收集的数据进行比较。
向1647名继续接受牛津计划生育协会避孕研究随访的女性邮寄问卷,并另外联系424名女性进行个人访谈。回复率分别为91%和79%。
91%的妊娠匹配成功。回忆中位数时间为14年(四分位间距为11 - 16年)。在组水平上,以活产累积百分比分布呈现的两种信息来源之间发现了非常好的一致性。回忆时间较长(>14年)时的结果与较短回忆时间时至少一样好。存在有限程度的数字表现。在个体水平上,一些错误分类很明显,这对统计效力有影响。对于临床不孕症(12个月内未受孕)的检测,敏感性在67% - 91%范围内,特异性为92% - 96%。格式、回忆持续时间、分娩年龄、出生年份、产次、社会阶层、吸烟习惯、最后避孕方法以及结局(是否活产)的差异通常较小,且无统计学意义。
受孕时间是评估两性生殖功能的一种敏感方法。使用简短问卷,通过较长时间的回忆,可以回顾性地得出组水平的有效数据。