Lewis S F, Garver D L
Department of Psychiatry, University of Arizona School of Medicine, Tucson VAMC 85623, USA.
J Psychiatr Res. 1995 Jan-Feb;29(1):5-11. doi: 10.1016/0022-3956(94)00033-n.
Patients with schizophrenia have been described as having deficits in the ability to recognize facial expressions of emotion. We report the results of a study on the effects of global psychopathology, positive and negative symptoms, diagnostic subtype, and antipsychotic medications, on the ability of subjects with schizophrenia to recognize facial affect. Eighteen SCID diagnosed patients with schizophrenia and ten matched controls were evaluated at a drug-free baseline for ability to identify facial expression expressed in a standardized series of photographs, with concurrent measures of global psychopathology, and positive and negative symptoms. At baseline patients were impaired in affect recognition relative to the normals, and impairment was not related to measures of psychopathology or positive or negative symptoms. Performance did not improve with antipsychotic treatment, and patients with paranoid schizophrenia had significantly better affect recognition abilities than non-paranoid patients.
精神分裂症患者被描述为在识别情感面部表情的能力方面存在缺陷。我们报告了一项关于整体精神病理学、阳性和阴性症状、诊断亚型以及抗精神病药物对精神分裂症患者识别面部情感能力影响的研究结果。对18名经结构性临床访谈（SCID）诊断为精神分裂症的患者和10名匹配的对照组在无药物基线状态下进行评估，以确定他们识别一系列标准化照片中所表达面部表情的能力，同时测量整体精神病理学以及阳性和阴性症状。在基线时，与正常人相比，患者在情感识别方面存在缺陷，且这种缺陷与精神病理学测量或阳性或阴性症状无关。抗精神病药物治疗后表现并未改善，偏执型精神分裂症患者的情感识别能力明显优于非偏执型患者。
