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左冠状动脉完全闭塞。发病率及处理

Total occlusion of left coronary artery. Incidence and management.

作者信息

Crosby I K, Wellons H A, Burwell L

出版信息

J Thorac Cardiovasc Surg. 1979 Mar;77(3):389-91.

PMID:762982
Abstract

From July 1, 1972, to Jan. 1, 1978, 527 patients underwent coronary revascularization. In four (0.76%) of these patients arteriography demonstrated total occlusion of the left main coronary artery. The incidence of acquired occlusion of the left coronary artery encountered in the cardiac catheterization laboratory during the same period was 0.17% in patients undergoing coronary arteriography. Literature review reveals 13 patients with total occlusion of the left coronary artery, and only seven of these were treated operatively, some with suboptimal results. With an average of three grafts per patient, all four of our patients are in Class I of the New York Association an average of 23 months postoperatively. These patients were dramatically symptomatic preoperatively, and their clinical management in terms of pharmacologic or mechanical intraoperative support was no different from that of patients with critical stenosis of the left main coronary artery. This report documents the incidence of left coronary artery occlusion encountered in clinical practice. This incidence should not be as rare as the literature review suggests.

摘要

1972年7月1日至1978年1月1日期间,527例患者接受了冠状动脉血运重建术。其中4例(0.76%)患者的血管造影显示左主干冠状动脉完全闭塞。同期在心脏导管实验室接受冠状动脉造影的患者中,左冠状动脉获得性闭塞的发生率为0.17%。文献回顾发现13例左冠状动脉完全闭塞患者,其中仅7例接受了手术治疗,部分效果欠佳。我们的4例患者平均每人接受了3次移植手术,术后平均23个月时均处于纽约心脏协会心功能I级。这些患者术前症状明显,就术中药物或机械支持方面的临床管理而言,与左主干冠状动脉严重狭窄患者并无不同。本报告记录了临床实践中遇到的左冠状动脉闭塞发生率。这一发生率不应像文献回顾所显示的那样罕见。

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