Brook I
Department of Pediatrics, Georgetown University School of Medicine, Washington, DC, USA.
J Med Microbiol. 1995 Aug;43(2):92-8. doi: 10.1099/00222615-43-2-92.
From 1974 to 1990, 336 Bacteroides isolates were obtained from 312 specimens from 274 patients. They comprised 180 (54%) B. fragilis isolates, 55 (16%) B. theta-iotaomicron, 36 (11%) B. vulgatus, 34 (10%) B. distasonis, 21 (6%) B. ovatus and 10 (3%) B. uniformis. Infections in 253 (92%) patients were polymicrobial, but in 21 (8%) children, a Bacteroides sp. was isolated in pure culture. Most Bacteroides isolates were from peritoneal fluid (114), abscesses (110), wound infections (20), blood cultures (10) and from patients with pneumonia (14) or chronic otitis media (8). Predisposing conditions were present in 145 (53%) children; these were previous surgery (46), trauma (28), malignancy (21), prematurity (19), immunodeficiency (18), steroid therapy (12) foreign body (10), diabetes (9) and sickle cell disease (7). The micro-organisms isolated most commonly mixed with Bacteroides spp. were anaerobic cocci (221), Escherichia coli (122), Fusobacterium spp. (38) and Clostridium spp. (30). All patients received antimicrobial therapy in conjunction with surgical drainage or correction of pathology in 197 (72%) cases. All but 12 (5%) patients recovered. These data illustrate the importance of Bacteroides spp. in infections in children.
1974年至1990年期间，从274例患者的312份标本中分离出336株拟杆菌。其中包括180株（54%）脆弱拟杆菌、55株（16%）θ-艾托美隆拟杆菌、36株（11%）普通拟杆菌、34株（10%）解脲拟杆菌、21株（6%）卵形拟杆菌和10株（3%）单形拟杆菌。253例（92%）患者的感染为混合菌感染，但21例（8%）儿童患者的标本中，拟杆菌为纯培养分离株。大多数拟杆菌分离株来自腹腔积液（114株）、脓肿（110株）、伤口感染（20株）、血培养（10株）以及肺炎（14例）或慢性中耳炎（8例）患者。145例（53%）儿童存在易感因素；包括既往手术史（46例）、外伤（28例）、恶性肿瘤（21例）、早产（19例）、免疫缺陷（18例）、类固醇治疗（12例）、异物（10例）、糖尿病（9例）和镰状细胞病（7例）。最常与拟杆菌属混合分离出的微生物为厌氧球菌（221株）、大肠埃希菌（122株）、梭杆菌属（杆菌属）（38株）和梭菌属（30株）。197例（72%）患者在接受抗菌治疗的同时进行了手术引流或病理纠正。除12例（5%）患者外，其余均康复。这些数据说明了拟杆菌属在儿童感染中的重要性。
