Teutsch S M, Juranek D D, Sulzer A, Dubey J P, Sikes R K
N Engl J Med. 1979 Mar 29;300(13):695-9. doi: 10.1056/NEJM197903293001302.
In October, 1977, an outbreak of toxoplasmosis occurred in patrons of a riding stable in Atlanta, Georgia; 37 became ill with toxoplasmosis or had serologic evidence by indirect fluorescent-antibody test of acute infection with Toxoplasma gondii (titer greater than or equal to 1:4096 or a positive fluorescent-antibody test for toxoplasma antibodies). Forty-nine additional patrons did not become ill. Two of the three adult cats from the stable were seropositive for toxoplasma, which was also recovered from the tissues of two kittens and four mice trapped near the stable. Patrons who spent most of their time at the end of the stable where a cat had defecated had the highest incidence of infection. Patrons who attended the stable daily had a higher attack rate than those who attended less frequently. No common meals were consumed, and dietary histroy eliminated meat as the source of infection. The data suggest that toxoplasma oocysts were the source of the infection.
1977年10月,佐治亚州亚特兰大市一家马术训练场的顾客中爆发了弓形虫病疫情;37人感染了弓形虫病,或通过间接荧光抗体试验有急性感染刚地弓形虫的血清学证据(滴度大于或等于1:4096,或弓形虫抗体荧光抗体试验呈阳性)。另外49名顾客未患病。马场的三只成年猫中有两只弓形虫血清呈阳性,在马场附近捕获的两只小猫和四只老鼠的组织中也检测到了弓形虫。大部分时间待在马场里有猫排便区域的顾客感染率最高。每天去马场的顾客发病率高于不常去的顾客。顾客们没有共同用餐,饮食史排除了肉类作为感染源。数据表明,弓形虫卵囊是感染源。