Blankensteijn J D, Gertler J P, Brewster D C, Cambria R P, LaMuraglia G M, Abbott W M
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA.
Eur J Vasc Endovasc Surg. 1995 May;9(4):375-82. doi: 10.1016/s1078-5884(05)80003-6.
To evaluate a number of currently available methods for intraoperative assessment of infrainguinal bypass grafts (IBG) in terms of detecting technical errors and predicting graft failure.
Prospective open clinical study.
Forty-nine patients undergoing 54 consecutive IBG were studied. Intraoperatively, the following measurements were performed: distal pulse palpation (DPP), continuous wave Doppler (CWD), pulse volume recording (PVR), and ultrasonic volume flowmetry (UVF), followed by intraoperative angiography of the entire graft and runoff vessels. The outflow resistance was graded according to the guidelines of the Society for Vascular Surgery and International Society for Cardiovascular Surgery (SVS/ISCVS runoff score). Graft patency was determined noninvasively (PVR, colour Duplex) up to 12 months following surgery. Predictive values and likelihood ratios for the intraoperative tests in detecting a technical problem during the bypass procedure and in predicting early graft failure were calculated.
There were five immediate revisions for problems detected intraoperatively. Angiography did not identify any additional problems but assisted in the correct location of the problems detected by the other tests. DPP and CWD were highly significant indicators of the need for revision with likelihood ratios for a positive test of 14.7 (p < 0.01) and 12.3 (p < 0.01) respectively. PVR did not achieve statistical significance in this respect. None of the intraoperative tests was a statistically significant predictor of early graft failure. The SVS/ISCVS runoff score, on the other hand, predicted early failure with a PPV of 33% (likelihood ratio for a positive test of 4.9, p < 0.05). None of the grafts with a perfect SVS/ISCVS runoff score (n = 39) failed in the first postoperative month.
Simple CWD insonation of graft and anastomoses is the best intraoperative indicator for technical inadequacies after IBG. Routine intraoperative angiography is not necessary and intraoperative anatomical imaging may be reserved for situations in which noninvasive documentation of technical success is absent. Contrary to the intraoperative haemodynamic test results, the SVS/ISCVS runoff score is a good predictor of early graft failure.
评估目前一些可用于术中评估下肢旁路移植血管(IBG)的方法,以检测技术失误并预测移植血管失败情况。
前瞻性开放性临床研究。
对49例接受54次连续IBG手术的患者进行研究。术中进行以下测量:远端脉搏触诊(DPP)、连续波多普勒(CWD)、脉搏容积记录(PVR)和超声容积血流测定(UVF),随后对整个移植血管及流出道血管进行术中血管造影。根据血管外科学会和国际心血管外科学会(SVS/ISCVS流出道评分)指南对流出道阻力进行分级。术后12个月内通过无创方法(PVR、彩色双功超声)确定移植血管通畅情况。计算术中检测旁路手术期间技术问题及预测早期移植血管失败的预测值和似然比。
因术中检测到的问题进行了5次即刻翻修。血管造影未发现任何其他问题,但有助于确定其他检测所发现问题的正确位置。DPP和CWD是需要翻修的高度显著指标,阳性检测的似然比分别为14.7(p<0.01)和12.3(p<0.01)。PVR在这方面未达到统计学显著性。术中检测均不是早期移植血管失败的统计学显著预测指标。另一方面,SVS/ISCVS流出道评分预测早期失败的阳性预测值为33%(阳性检测的似然比为4.9,p<0.05)。SVS/ISCVS流出道评分完美(n = 39)的移植血管在术后第一个月均未失败。
对移植血管和吻合口进行简单的CWD探测是IBG术后技术缺陷的最佳术中指标。常规术中血管造影不必要,术中解剖成像可保留用于缺乏技术成功的无创记录的情况。与术中血流动力学检测结果相反,SVS/ISCVS流出道评分是早期移植血管失败的良好预测指标。