Wolff S P
University College London Medical School, UK.
Doc Ophthalmol. 1994;88(3-4):201-4. doi: 10.1007/BF01203674.
The idea that UV radiation causes cataract has superficial biological plausibility based upon studies of UV-B on lens components, whole lenses and experimental animals. However, epidemiological studies on man, particularly geographical studies, are highly confounded by socioeconomic factors and yield little information. Population-based exposure-cataract studies are preferable since UV incidence versus UV exposure can be weighted with respect to risk and protective factors. However, the cataractogenic potency of UV seems to be low and certainly lower than the cataractogenic potency of factors such as repeated diarrhoea so that it is doubtful whether a clear answer to the question 'Does UV cause cataract' will ever be provided.
基于对紫外线B对晶状体成分、整个晶状体和实验动物的研究，紫外线辐射会导致白内障这一观点在生物学上有一定的表面合理性。然而，对人类的流行病学研究，尤其是地理研究，受到社会经济因素的严重干扰，几乎没有提供什么信息。基于人群的暴露-白内障研究更可取，因为紫外线发病率与紫外线暴露情况可以根据风险和保护因素进行加权。然而，紫外线的致白内障效力似乎较低，肯定低于反复腹泻等因素的致白内障效力，因此对于“紫外线会导致白内障吗”这个问题能否得到明确答案仍存疑问。
