Tramadol (Zydol-Searle) is a centrally acting opioid analgesic newly marketed in the UK for use by mouth or injection. It is licensed for the prevention and treatment of moderate to severe pain. The manufacturer claims that it causes less constipation and respiratory depression than conventional opioids and that it offers a special "dual action". We examine the claims and consider the place of tramadol.
曲马多(赛诺菲公司的奇曼丁)是一种中枢性阿片类镇痛药,最近在英国上市,可口服或注射使用。它被批准用于预防和治疗中度至重度疼痛。制造商声称,与传统阿片类药物相比,它引起的便秘和呼吸抑制较少,并且具有特殊的“双重作用”。我们对这些说法进行了研究,并探讨了曲马多的地位。