Richter W O
Medizinische Klinik II, Klinikum Grosshadern der Universität München.
Fortschr Med. 1995 Jun 10;113(16):243-6.
Both the levels of fat and cholesterol in the diet and its fatty acid composition influence the CAD risk. In recent years, it has been recognized, however, that a high percentage of polyunsaturated fatty acids can have a negative effect, for example on the immune system. It is therefore recommended that 7-10% of dietary energy be consumed in the form of polyunsaturated and saturated fatty acids, but 10-15% as mono-unsaturated fatty acids. In view of the associated favorable effect on CAD mortality, an increase in consumption of sea fish can now be recommended, while the benefits of consuming high doses of fish oil has not been proven. The positive effect of a fiber-rich diet is largely due to the associated decrease in consumption of saturated fatty acids. An additional cholesterol-lowering effect has been demonstrated only for particular substances, for example oat bran. Numerous other dietary constituents, such as alcohol, salt or antioxidants, may also have effects on atherogenesis.
饮食中的脂肪和胆固醇水平及其脂肪酸组成都会影响患冠心病的风险。然而,近年来人们已经认识到,高比例的多不饱和脂肪酸可能会产生负面影响,比如对免疫系统的影响。因此,建议饮食能量的7%-10%以多不饱和脂肪酸和饱和脂肪酸的形式摄入,而单不饱和脂肪酸的摄入量应为10%-15%。鉴于海鱼对冠心病死亡率有相关的有利影响,现在建议增加海鱼的摄入量,而高剂量鱼油摄入的益处尚未得到证实。富含纤维的饮食产生积极作用很大程度上是因为饱和脂肪酸的摄入量随之减少。仅特定物质(如燕麦麸)已被证明具有额外的降胆固醇作用。许多其他饮食成分,如酒精、盐或抗氧化剂,也可能对动脉粥样硬化的形成产生影响。