Zaher T F
Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Int Urol Nephrol. 1998;30(2):193-6. doi: 10.1007/BF02550576.
A study comparing intracorporeal injection of prostaglandin E1 (one-drug solution) and papaverine plus prostaglandin E1 (2-drug solution) for treatment of impotence.
A total of 100 impotent patients had intracorporeal injections of the one-drug and 2-drug solution alternatively in 3 sessions. The quality and duration of erections were assessed.
Seventy-five per cent of the patients developed full erection with the 2-drug solution compared to 50% with the one-drug solution. The average duration of erections was 60 minutes and 45 minutes, respectively. The complication rate was higher for the 2-drug solution.
Papaverine plus prostaglandin E1 is superior to prostaglandin E1 alone for treatment of impotence, but has a higher rate of complications. Intracavemous injection of vasoactive drugs is a very effective and important way for treatment of impotence. Papaverine plus prostaglandin E1 had been used for treatment of impotence alone or combined. A blind study was done to compare efficiency and complication rates of intracavemous injection of papaverine plus prostaglandin E1 (2-drug solution) with prostaglandin E1 alone.
一项比较前列腺素E1体内注射（单药溶液）和罂粟碱加前列腺素E1（双药溶液）治疗阳痿的研究。
总共100例阳痿患者在3个疗程中交替进行单药溶液和双药溶液的体内注射。对勃起的质量和持续时间进行评估。
使用双药溶液的患者中有75%出现完全勃起，而使用单药溶液的患者中这一比例为50%。勃起的平均持续时间分别为60分钟和45分钟。双药溶液的并发症发生率更高。
罂粟碱加前列腺素E1治疗阳痿优于单独使用前列腺素E1，但并发症发生率更高。海绵体内注射血管活性药物是治疗阳痿非常有效且重要的方法。罂粟碱加前列腺素E1已单独或联合用于治疗阳痿。进行了一项盲法研究，以比较海绵体内注射罂粟碱加前列腺素E1（双药溶液）与单独使用前列腺素E1的疗效和并发症发生率。
