Connolly J A, Miller B, Bretan P N
Department of Urology, University of California School of Medicine, San Francisco, USA.
J Urol. 1995 Sep;154(3):1153-5.
We assessed the long-term efficacy of renal transplantation in patients with posterior urethral valves.
We reviewed the outcome in 23 patients with posterior urethral valves who underwent renal transplantation since 1979.
Graft survival was 69% at 5 years and 63% at 10 years. Seven patients with followup of 7 years or longer had a mean serum creatinine level of 1.5 mg/dl. Three patients (13%) demonstrated significant bladder dysfunction postoperatively.
Renal transplantation into a valve bladder is not associated with an abnormally high rate of failure. Deterioration of graft function secondary to lower urinary tract dysfunction is uncommon, with the majority of patients able to use the unmodified native bladder as a receptacle for the transplanted kidney.
我们评估了后尿道瓣膜患者肾移植的长期疗效。
我们回顾了自1979年以来接受肾移植的23例后尿道瓣膜患者的治疗结果。
移植肾5年生存率为69%，10年生存率为63%。7例随访7年或更长时间的患者血清肌酐平均水平为1.5mg/dl。3例患者（13%）术后出现明显膀胱功能障碍。
将肾移植到有瓣膜的膀胱中并不会导致异常高的失败率。继发于下尿路功能障碍的移植肾功能恶化并不常见，大多数患者能够使用未改良的天然膀胱作为移植肾的储存器。
