Gupta M, Bolton D M, Irby P, Hubner W, Wolf J S, Hattner R S, Stoller M L
Department of Urology, University of California School of Medicine, San Francisco, USA.
J Urol. 1995 Sep;154(3):947-50.
We studied the effect of second generation lithotripsy on renal function.
We evaluated 42 patients with unilateral renal calculi by nuclear renography, serum creatinine levels, renal ultrasonography and plain radiographs.
There was no significant change in glomerular filtration rate at 1 or 3 months. Split function of the treated kidneys was lower at 1 month (mean 47.2%, p = 0.01) and 3 months (47.3%, p = 0.01) than before treatment (49.1%). A greater than 5% decrease in split function of the treated kidney occurred at 1 month in 6 patients (16.2%) and at 3 months in 3. Of the patients 23 (62.2%) were stone-free and 11 had residual fragments less than 4 mm., with a 19% retreatment rate for an overall success rate of 91.9%.
Newer generation lithotriptors may limit renal damage while permitting satisfactory treatment of renal calculi.
我们研究了第二代碎石术对肾功能的影响。
我们通过核肾图、血清肌酐水平、肾脏超声检查和腹部平片对42例单侧肾结石患者进行了评估。
1个月或3个月时肾小球滤过率无显著变化。治疗后肾脏的分肾功能在1个月时（平均47.2%，p = 0.01）和3个月时（47.3%，p = 0.01）低于治疗前（49.1%）。治疗后肾脏分肾功能下降超过5%的情况在1个月时有6例患者（16.2%）出现，3个月时有3例。23例（62.2%）患者结石清除，11例有小于4mm的残留碎片，再治疗率为19%，总成功率为91.9%。
新一代碎石机可能在允许满意治疗肾结石的同时限制肾脏损害。
