Fujii Y, Higashi Y, Owada F, Okuno T, Noro A, Arisawa C
Department of Urology, Omiya Red Cross Hospital.
Nihon Hinyokika Gakkai Zasshi. 1995 Jul;86(7):1261-5. doi: 10.5980/jpnjurol1989.86.1261.
The response of bone metastatic lesions to endocrine therapy was assessed by repeated magnetic resonance imaging (MRI) and an isotope bone scan after an average period of 7.0 months (2-10 months) in 12 patients with prostate cancer. MRI used both T1-weighted spin echo technique and short TI IR (STIR) sequence. Of 7 patients with hormone-dependent cancer, the bone metastatic lesions resolved or became vague in all patients on STIR image, while in only 4 and 3 on T1-weighted image and bone scan, respectively. Of 5 patients with hormone-refractory cancer, the lesions progressed on both MRI and bone scan in all patients except one who had initially had diffusely metastatic lesions of systemic bone. The results indicate that STIR image of MRI is helpful for the therapeutic evaluation of bone lesions.
通过对12例前列腺癌患者平均7.0个月（2 - 10个月）后进行重复磁共振成像（MRI）和同位素骨扫描，评估骨转移病灶对内分泌治疗的反应。MRI采用T1加权自旋回波技术和短TI反转恢复（STIR）序列。在7例激素依赖性癌症患者中，所有患者的骨转移病灶在STIR图像上均消失或变得模糊，而在T1加权图像和骨扫描上分别只有4例和3例出现这种情况。在5例激素难治性癌症患者中，除1例最初有全身骨骼弥漫性转移病灶的患者外，所有患者的病灶在MRI和骨扫描上均进展。结果表明，MRI的STIR图像有助于骨病灶的治疗评估。
