Potapova A V, Aprosina Z G, Kosminkova E N, Varshavskiĭ V A
Ter Arkh. 1995;67(5):31-3.
The paper reports 4 cases of tubulointerstitial nephritis (TIN) in chronic diffuse diseases of the liver (CDDL). The latter comprised such conditions of virus etiology as chronic active hepatitis, chronic lobular hepatitis. TIN presented with pronounced renal tubular affections: defects of concentration capacity, distal renal tubular acidosis, renal diabetes insipidus. In 3 cases renal lesions occurred 1 and 6 years prior to CDDL detection. TIN pathogenesis in CDDL of viral etiology is discussed.
本文报道了4例慢性弥漫性肝病（CDDL）合并肾小管间质性肾炎（TIN）的病例。后者包括病毒病因引起的慢性活动性肝炎、慢性小叶性肝炎等疾病。TIN表现为明显的肾小管病变：浓缩功能缺陷、远端肾小管性酸中毒、肾性尿崩症。3例患者的肾脏病变发生在CDDL确诊前1年和6年。本文还讨论了病毒病因引起的CDDL中TIN的发病机制。
