Madreperla S A, McCuen B W, Hickingbotham D, Green W R
Duke Eye Center, Durham, North Carolina, USA.
Am J Ophthalmol. 1995 Aug;120(2):197-207. doi: 10.1016/s0002-9394(14)72608-x.
To determine the ultrastructural characteristic of the operculum associated with macular holes.
We developed instrumentation and a technique to capture the operculum observed with macular holes. Two opercula were studied by transmission electron microscopy.
The two specimens were attached to a layer of native collagen identified as cortical vitreous and were composed primarily of Mueller cells and fibrous astrocytes without adjacent inner limiting membrane. No distinct retinal neuronal tissue was present.
Our findings indicate that proliferation of fibrous astrocytes and Mueller cells occurs with the formation of a macular hole, that this reparative tissue may be dislodged, and it is the reparative tissue that previously has been interpreted as an operculum.
确定与黄斑裂孔相关的盖膜的超微结构特征。
我们开发了仪器和技术来捕获在黄斑裂孔中观察到的盖膜。通过透射电子显微镜研究了两个盖膜。
这两个标本附着在一层被鉴定为皮质玻璃体的天然胶原层上，主要由米勒细胞和纤维性星形胶质细胞组成，没有相邻的内界膜。不存在明显的视网膜神经元组织。
我们的研究结果表明，纤维性星形胶质细胞和米勒细胞的增殖与黄斑裂孔的形成有关，这种修复组织可能会脱落，并且之前被解释为盖膜的正是这种修复组织。
