Leen M M, Moster M R, Katz L J, Terebuh A K, Schmidt C M, Spaeth G L
Department of Ophthalmology, University of Washington School of Medicine, Seattle, USA.
Arch Ophthalmol. 1995 Aug;113(8):1050-5. doi: 10.1001/archopht.1995.01100080102036.
We describe our experience with intrableb autologous blood injection to manage over-filtering and leaking blebs. Autologous blood was injected into 12 thin cystic filtration blebs of 12 eyes. Indications for blood injection included symptomatic hypotony in five eyes, hypotony associated with bleb leakage in five eyes, and bleb leakage without hypotony in two eyes. Seven eyes (58.3%) were classified as successes and five eyes (41.7%) were classified as failures. The mean (+/- SD) follow-up was 6.8 +/- 2.6 months. Among the eyes classified as successes, a significant increase was noted in intraocular pressure and visual acuity by a mean (+/- SD) of 5.1 +/- 2.9 mm Hg and 5.3 +/- 2.1 lines, respectively. Bleb leakage resolved in four of seven eyes. The most common complication was hyphema formation. Injection of autologous blood into a filtration bleb is an alternative procedure for management of excessive filtration or bleb leakage in selected patients.
我们描述了运用滤过泡内自体血注射来处理滤过过度和滤过泡渗漏的经验。将自体血注射到12只眼的12个薄壁囊性滤过泡中。注射血液的指征包括5只眼有症状性低眼压，5只眼低眼压伴有滤过泡渗漏，2只眼滤过泡渗漏但无低眼压。7只眼（58.3%）被判定为成功，5只眼（41.7%）被判定为失败。平均（±标准差）随访时间为6.8±2.6个月。在判定为成功的眼中，眼压和视力显著提高，平均（±标准差）分别提高了5.1±2.9mmHg和5.3±2.1行。7只眼中有4只眼的滤过泡渗漏得到解决。最常见的并发症是前房积血形成。向滤过泡内注射自体血是治疗部分患者滤过过度或滤过泡渗漏的一种替代方法。
