Wise J B
Baptist Medical Center of Oklahoma, Oklahoma City.
Arch Ophthalmol. 1993 Jun;111(6):827-30. doi: 10.1001/archopht.1993.01090060115034.
To treat chronic hypotony with decreased vision after filtration surgery.
After observation from 3 1/2 to 13 months with no spontaneous improvement, eyes were treated with the experimental therapy and followed up closely to determine the results.
Four eyes with chronic hypotony, selected from a series of 125 eyes receiving trabeculectomy augmented by intraoperative mitomycin. All eyes had posterior chamber pseudophakia. All eyes had postoperative laser cutting of sutures holding the scleral flap of the trabeculectomy.
After administration of topical prophylactic 0.3% ciprofloxacin hydrochloride and topical anesthetic, the bleb was inflated with whole autologous blood through a 27-gauge needle passed subconjunctivally into the bleb.
Change in intraocular pressure, change in vision, change in choroidal detachment, any type of complication.
Average intraocular pressure increased from 5.5 to 8.2 mm Hg. Average vision improved from 20/148 to 20/33. In two eyes with choroidal detachment, the detachment absorbed in one eye and decreased in the other. No complications occurred.
Intrableb injection of autologous blood deserves further study as a possible treatment for hypotony following filtration.
治疗滤过性手术后出现视力下降的慢性低眼压。
在观察3个半月至13个月且无自发改善后，对眼睛进行实验性治疗并密切随访以确定结果。
从125例行小梁切除术并术中使用丝裂霉素的患者系列中选出4只患有慢性低眼压的眼睛。所有眼睛均有后房型人工晶状体。所有眼睛术后均进行了激光切开小梁切除巩膜瓣的缝线。
在局部应用预防性0.3%盐酸环丙沙星和局部麻醉后，通过一根27号针头经结膜下刺入滤泡，向滤泡内注入全自体血。
眼压变化、视力变化、脉络膜脱离变化、任何类型的并发症。
平均眼压从5.5毫米汞柱升至8.2毫米汞柱。平均视力从20/148提高到20/33。在两只患有脉络膜脱离的眼睛中，一只眼睛的脱离吸收，另一只眼睛的脱离减轻。未发生并发症。
滤泡内注射自体血作为滤过性手术后低眼压的一种可能治疗方法值得进一步研究。
