Ikeda Y, Mori M, Kamakura T, Haraguchi Y, Saku M, Sugimachi K
Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Br J Cancer. 1995 Aug;72(2):424-6. doi: 10.1038/bjc.1995.349.
The data on 912 patients with early cancer and 1245 with advanced cancer who were seen between 1971 and 1990 were compared. The incidence of undifferentiated-type cancer increased significantly in patients with advanced gastric cancer, but not in patients with early gastric cancer. When the histological types were compared with regard to sex, age and location in patients with early gastric cancer the undifferentiated type was found to increase only in males, while in patients with advanced gastric cancer the undifferentiated type increased in both sexes as well as in younger patients and in both the upper and middle third of the stomach. These differences in the trends between early and advanced cancers are probably due to the different degrees of diagnostic accuracy for the early detection of histological types.
对1971年至1990年间就诊的912例早期癌症患者和1245例晚期癌症患者的数据进行了比较。未分化型癌症的发生率在进展期胃癌患者中显著增加，但在早期胃癌患者中未增加。在比较早期胃癌患者的组织学类型与性别、年龄及部位时，发现未分化型仅在男性中增加，而在进展期胃癌患者中，未分化型在男女两性、年轻患者以及胃的上三分之一和中三分之一部位均增加。早期和进展期癌症之间这些趋势的差异可能是由于组织学类型早期检测的诊断准确性不同所致。
