Mori M, Kitagawa S, Iida M, Sakurai T, Enjoji M, Sugimachi K, Ooiwa T
Cancer. 1987 May 15;59(10):1758-66. doi: 10.1002/1097-0142(19870515)59:10<1758::aid-cncr2820591014>3.0.co;2-v.
A clinicopathologic study was done on 21 cases of early carcinoma of the gastric cardia. The disease was preponderant in men, with a male-female ratio of 17:4. Five patients had no symptoms, while the other 16 had epigastric pain, epigastric discomfort, or other symptoms. Melena or hematemesis occurred in five patients. The first detection was made by barium study in 16 and by endoscopy in five. Detailed examinations using double-contrast radiography in both the prone right anterior oblique and supine left lateral projections were useful to detect the early carcinoma of the gastric cardia. All depressed-type carcinomas were incidentally detected during endoscopic examinations of benign peptic ulcers, therefore, whenever endoscopic examinations are being done for other entities, all the stomach including the cardia should be examined, carefully and continuously. Compared with early carcinomas of the other areas of the stomach, grossly elevated and histologically well-differentiated early carcinomas were more common in the gastric cardia. In the mucosa adjacent to the carcinoma, chronic gastritis was apparent in almost all cases, although intestinal metaplasia was found less frequently than in other areas of the stomach.
对21例早期贲门癌患者进行了临床病理研究。该疾病在男性中更为常见，男女比例为17:4。5例患者无症状，其余16例有上腹部疼痛、上腹部不适或其他症状。5例患者出现黑便或呕血。首次检测中，16例通过钡餐检查发现，5例通过内镜检查发现。采用俯卧右前斜位和仰卧左外侧位双对比造影进行详细检查，有助于检测早期贲门癌。所有凹陷型癌均在内镜检查良性消化性溃疡时偶然发现，因此，在对其他疾病进行内镜检查时，应仔细并持续检查包括贲门在内的整个胃部。与胃其他部位的早期癌相比，胃贲门处大体隆起且组织学高分化的早期癌更为常见。在癌旁黏膜中，几乎所有病例均可见慢性胃炎，尽管肠化生的发生率低于胃其他部位。
