Guerreiro M, Castro-Caldas A, Martins I P
Language Research Laboratory, Centro de Estudos Egas Moniz, Hospital de Santa Maria, Lisbon, Portugal.
Brain Lang. 1995 Jun;49(3):280-8. doi: 10.1006/brln.1995.1034.
The case of a 56-year-old woman who became aphasic following a right temporoparietal lesion is reported. At the age of 2, this woman had an acute infantile hemiplegia on the right side of the body and it was reported by relatives that a deterioration of language was also noted. There was a slow recovery of these deficits and she was considered as having normal language only at age 7. Although it is difficult to be sure about the hand preference of the patient before the stroke at age 2, the relatives were quite positive saying, that she previously preferred the right hand and that she became left handed. The CT scan showed an old left frontal ischemic lesion and a recent right temporoparietal lesion. This case illustrates the ability of the right hemisphere to take over functions of the left when a left lesion occurs in early stages of language acquisition. Although this is an accepted model for recovery, this is the only case in the literature with a documented early focal lesion of the left hemisphere. Other evidence comes from studies performed in populations where severe epilepsy may contribute to particular functional organization.
报告了一名56岁女性的病例，该女性在右侧颞顶叶病变后出现失语。这名女性在2岁时患急性小儿偏瘫，累及身体右侧，据亲属报告，当时还发现其语言功能有所退化。这些缺陷恢复缓慢，直到7岁时她的语言才被认为正常。虽然很难确定该患者在2岁中风前的利手情况，但亲属非常肯定地表示，她之前惯用右手，中风后变成了左利手。CT扫描显示左侧额叶有陈旧性缺血性病变，右侧颞顶叶有近期病变。该病例说明了在语言习得早期阶段左侧发生病变时，右侧半球接管左侧功能的能力。尽管这是一种公认的恢复模式，但这是文献中唯一有记录的早期左侧半球局灶性病变的病例。其他证据来自对严重癫痫可能导致特殊功能组织的人群进行的研究。
