Sherman R A, Wyle F, Vulpe M
Medical Service, VA Medical Center, Long Beach, CA 90822, USA.
J Spinal Cord Med. 1995 Apr;18(2):71-4. doi: 10.1080/10790268.1995.11719382.
For centuries, maggot therapy (MT) has been recognized as an aid to wound healing. By including live blowfly larvae in wound dressings, earlier physicians noted thorough debridement which hastened wound healing. We initiated a prospective controlled study to evaluate the utility of maggot therapy for treating pressure ulcers in spinal cord injury patients in the modern era. Eight of our patients received MT after a baseline assessment of healing under conventional therapy (defined as any therapy prescribed by the patient's primary care team). Surface area, tissue quality and healing rates were monitored weekly. MT debrided most of the necrotic wounds within one week, which was more rapid than all other non-surgical methods. Wound healing was more rapid during MT than during antecedent conventional therapy (p = 0.01). No complications were seen. We have demonstrated that MT can be beneficial in the treatment of pressure ulcers in persons with spinal cord injuries. MT was significantly more effective and efficient than the current, conventional treatment alternatives being used. MT was also safe, simple and inexpensive. MT can be a valuable modality in the treatment of pressure ulcers.
几个世纪以来,蛆虫疗法(MT)一直被认为有助于伤口愈合。早期医生通过在伤口敷料中加入活的绿头苍蝇幼虫,注意到其能进行彻底清创,从而加速伤口愈合。我们开展了一项前瞻性对照研究,以评估蛆虫疗法在现代治疗脊髓损伤患者压疮方面的效用。在对我们的8名患者进行常规治疗(定义为患者初级保健团队开具的任何治疗方法)下的愈合情况进行基线评估后,给予他们蛆虫疗法。每周监测伤口表面积、组织质量和愈合率。蛆虫疗法在一周内清除了大部分坏死伤口,比所有其他非手术方法都更快。蛆虫疗法期间的伤口愈合比之前的常规治疗更快(p = 0.01)。未观察到并发症。我们已经证明,蛆虫疗法对治疗脊髓损伤患者的压疮有益。蛆虫疗法比目前使用的传统治疗方法显著更有效且高效。蛆虫疗法也安全、简单且廉价。蛆虫疗法在治疗压疮方面可能是一种有价值的方法。