临床研究蛆虫疗法对慢性感染性病变的生物清创作用。
Clinical research on the bio-debridement effect of maggot therapy for treatment of chronically infected lesions.
机构信息
Department of Orthopedic Surgery, The First Affiliated Hospital, Dalian Medical University, Dalian, China.
出版信息
Orthop Surg. 2010 Aug;2(3):201-6. doi: 10.1111/j.1757-7861.2010.00087.x.
Abstract
OBJECTIVE
To evaluate the bio-debridement effect of maggot therapy for treating chronically infected lesions.
METHODS
A retrospective study was conducted of 25 patients with diabetic foot ulcers and 18 patients with pressure ulcers after spinal cord injury treated by maggot therapy or traditional dressing. Changes in the lesions were observed and bacterial cultures tested.
RESULTS
All ulcers healed completely. The times taken to achieve bacterial negativity, granulation and healing of lesions were all significantly shorter in the maggot therapy group than in the control group, both for diabetic foot ulcers (P < 0.05) and pressure ulcers (P < 0.05).
CONCLUSION
Maggot therapy is a safe and effective method for treating chronically infected lesions.
摘要
目的
评估蛆虫疗法治疗慢性感染性病变的生物清创效果。
方法
对 25 例糖尿病足溃疡患者和 18 例脊髓损伤后压疮患者进行回顾性研究，分别采用蛆虫疗法或传统敷料治疗。观察病变变化并进行细菌培养检测。
结果
所有溃疡均完全愈合。蛆虫疗法组细菌转阴、肉芽和病变愈合时间均明显短于对照组，糖尿病足溃疡（P<0.05）和压疮（P<0.05）均如此。
结论
蛆虫疗法是治疗慢性感染性病变的一种安全有效的方法。
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