Landh T
Department of Biophysical Sciences and Biomaterials, State University of New York at Buffalo, NY 14214, USA.
FEBS Lett. 1995 Aug 1;369(1):13-7. doi: 10.1016/0014-5793(95)00660-2.
The identification of evolutionary conserved membrane morphologies whose architecture is governed by cubic symmetry--cubic membranes--adds a new dimension to cell membrane functions and, perspicuously, to their role in subcellular space organization. Through analysis of electron micrographs, three families of cubic membranes have been unequivocally identified in which one or more (parallel) membranes, described by periodic cubic surfaces, partition space into two or more independent, albeit convoluted, subspaces of membrane potential determined dimensions. The choice of a particular cubic symmetry is suggested to be due to its activity. Here the architecture and function of multiple (> or = 3) subspace organization in classical membrane bound organelles is addressed. As it can be precisely determined with cubic membranes suggests that they can be employed as a reference morphology.
对进化上保守的、其结构由立方对称所支配的膜形态——立方膜——的识别，为细胞膜功能增添了一个新维度，而且显然也为其在亚细胞空间组织中的作用增添了新维度。通过对电子显微照片的分析，已明确识别出三类立方膜，其中一个或多个（平行的）膜由周期性立方表面描述，将空间分隔成两个或更多个独立的、尽管是曲折的、具有确定膜电位尺寸的子空间。特定立方对称的选择被认为是由于其活性。这里讨论了经典膜结合细胞器中多个（≥3）子空间组织的结构和功能。由于立方膜可以精确确定，这表明它们可被用作参考形态。
