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通过对睾丸活检获取的精子进行胞浆内注射实现受精和妊娠。

Fertilization and pregnancy achieved by intracytoplasmic injection of sperm retrieved from testicular biopsies.

作者信息

Abuzeid M I, Chan Y M, Sasy M A, Basata S, Beer M

机构信息

Department of Obstetrics and Gynecology, Hurley Medical Center, Flint, Michigan 48503, USA.

出版信息

Fertil Steril. 1995 Sep;64(3):644-6. doi: 10.1016/s0015-0282(16)57807-8.

DOI:10.1016/s0015-0282(16)57807-8
PMID:7641924
Abstract

OBJECTIVE

To determine if intracytoplasmic sperm injection using testicular sperm is effective in the treatment of infertile couples with obstructive azoospermia.

DESIGN

Case report.

SETTING

Tertiary care teaching medical center.

METHODS

Intracytoplasmic sperm injection was performed in two patients using testicular sperm after microsurgical epididymal sperm aspiration failed.

RESULTS

In both cases fertilization and embryos resulted. One patient conceived and delivered triplets. There was no evidence of chromosomal abnormality or congenital malformation.

CONCLUSIONS

Intracytoplasmic sperm injection using sperm extracted from testicular biopsy appears to be effective in the treatment of infertile couples with obstructive azoospermia when microsurgical sperm aspiration fails.

摘要

目的

确定采用睾丸精子进行卵胞浆内单精子注射对梗阻性无精子症不育夫妇的治疗效果。

设计

病例报告。

地点

三级护理教学医学中心。

方法

在两例患者中,显微外科附睾精子抽吸失败后,采用睾丸精子进行卵胞浆内单精子注射。

结果

两例均实现受精并形成胚胎。一名患者成功受孕并分娩三胞胎。无染色体异常或先天性畸形的证据。

结论

当显微外科精子抽吸失败时,采用睾丸活检提取的精子进行卵胞浆内单精子注射,对梗阻性无精子症不育夫妇似乎有效。

相似文献

1
Fertilization and pregnancy achieved by intracytoplasmic injection of sperm retrieved from testicular biopsies.通过对睾丸活检获取的精子进行胞浆内注射实现受精和妊娠。
Fertil Steril. 1995 Sep;64(3):644-6. doi: 10.1016/s0015-0282(16)57807-8.
2
Fertilizing capacity of epididymal and testicular sperm using intracytoplasmic sperm injection (ICSI).利用卵胞浆内单精子注射(ICSI)评估附睾精子和睾丸精子的受精能力。
Reprod Fertil Dev. 1995;7(2):281-92; discussion 292-3. doi: 10.1071/rd9950281.
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Testicular needle biopsy, open biopsy, epididymal aspiration and intracytoplasmic sperm injection in obstructive azoospermia.梗阻性无精子症的睾丸针吸活检、开放活检、附睾抽吸及卵胞浆内单精子注射
Hum Reprod. 1995 Oct;10(10):2595-9.
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Percutaneous epididymal sperm aspiration and intracytoplasmic sperm injection in the management of infertility due to obstructive azoospermia.
Fertil Steril. 1995 May;63(5):1038-42. doi: 10.1016/s0015-0282(16)57544-x.
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Fertilization and pregnancy outcome with intracytoplasmic sperm injection for azoospermic men.无精子症男性卵胞浆内单精子注射后的受精及妊娠结局
Hum Reprod. 1999 Mar;14(3):741-8. doi: 10.1093/humrep/14.3.741.
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Intracytoplasmic sperm injection for treatment of non-obstructive azoospermia.卵胞浆内单精子注射治疗非梗阻性无精子症。
Gynecol Endocrinol. 1997 Oct;11(5):335-9. doi: 10.3109/09513599709152558.
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High fertilization and pregnancy rate after intracytoplasmic sperm injection with spermatozoa obtained from testicle biopsy.采用经睾丸活检获取的精子进行卵胞浆内单精子注射后具有较高的受精率和妊娠率。
Hum Reprod. 1995 Jan;10(1):148-52. doi: 10.1093/humrep/10.1.148.
8
[Microsurgical epididymal sperm aspiration (MESA), testicular biopsy and intracytoplasmic sperm injection (ICSI) in the treatment of male infertility].[显微外科附睾精子抽吸术(MESA)、睾丸活检及卵胞浆内单精子注射术(ICSI)治疗男性不育症]
Prog Urol. 1999 Sep;9(4):696-702.
9
Outcome of intracytoplasmic sperm injection with testicular spermatozoa in obstructive and non-obstructive azoospermia.
Hum Reprod. 1996 May;11(5):1015-8. doi: 10.1093/oxfordjournals.humrep.a019288.
10
Intracytoplasmic sperm injection using microsurgically retrieved epididymal and testicular sperm.使用显微外科获取的附睾和睾丸精子进行胞浆内单精子注射。
Fertil Steril. 1996 Mar;65(3):566-72. doi: 10.1016/s0015-0282(16)58155-2.

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Human pregnancies after transfer of fresh (four- to eight-cell) versus frozen-thawed blastocysts resulting from intracytoplasmic sperm injection.卵胞浆内单精子注射后新鲜(4至8细胞)与冻融囊胚移植后的人类妊娠情况。
J Assist Reprod Genet. 1998 Aug;15(7):422-6. doi: 10.1007/BF02744935.
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Is vasectomy harmful to health?输精管切除术对健康有害吗?
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