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一项关于不孕患者红发颜色与子宫内膜异位症之间关联的前瞻性研究。

A prospective study on the association between red hair color and endometriosis in infertile patients.

作者信息

Woodworth S H, Singh M, Yussman M A, Sanfilippo J S, Cook C L, Lincoln S R

机构信息

Department of Obstetrics and Gynecology, University of Louisville School of Medicine, Kentucky, USA.

出版信息

Fertil Steril. 1995 Sep;64(3):651-2. doi: 10.1016/s0015-0282(16)57809-1.

DOI:10.1016/s0015-0282(16)57809-1
PMID:7641926
Abstract

OBJECTIVE

To determine if red-haired infertile women have an increased prevalence of endometriosis.

DESIGN

Prospective, nonblinded.

SETTING

Large, metropolitan, private hospital, associated with a university. Subspeciality care provided by reproductive endocrinologists.

PATIENTS

One hundred forty-three consecutive women undergoing laparoscopy or laparotomy for infertility.

INTERVENTIONS

Laser ablation of any endometriosis present.

MAIN OUTCOME MEASURE

Presence of endometriosis.

RESULTS

Of 143 women entered into the study, 12 had natural red hair. The ages of these women ranged between 23 and 41 years. Ten of 12 (83%) of the red-haired women were found to have endometriosis compared with 55 of 131 (42%) of nonredheads. By statistical analysis, the 95% confidence intervals for the presence of endometriosis in redheads was 55% to 100% versus 34% to 51% for nonredheads.

CONCLUSION

The results suggest an association between the occurrence of natural red hair and those factors that lead to the development of endometriosis.

摘要

目的

确定红发不孕女性子宫内膜异位症的患病率是否增加。

设计

前瞻性、非盲法。

地点

与一所大学相关的大型都市私立医院。由生殖内分泌学家提供专科护理。

患者

143名连续接受腹腔镜检查或剖腹手术以评估不孕情况的女性。

干预措施

对存在的任何子宫内膜异位症进行激光消融。

主要观察指标

子宫内膜异位症的存在情况。

结果

在纳入研究的143名女性中,有12名天生红发。这些女性的年龄在23岁至41岁之间。12名红发女性中有10名(83%)被发现患有子宫内膜异位症,相比之下,131名非红发女性中有55名(42%)患有该病。通过统计分析,红发女性患子宫内膜异位症的95%置信区间为55%至100%,而非红发女性为34%至51%。

结论

结果表明天生红发与导致子宫内膜异位症发生的因素之间存在关联。

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