Santema J G, Bourdrez P, Wallenburg H C
Department of Obstetrics and Gynecology, Erasmus University School of Medicine and Health Sciences, Rotterdam, The Netherlands.
Eur J Obstet Gynecol Reprod Biol. 1995 Jun;60(2):143-7. doi: 10.1016/0028-2243(95)02092-7.
To compare maternal and perinatal complications in triplet and twin pregnancies.
Case-controlled study in the setting of a University Hospital. Each pregnancy of a consecutive series of 40 triplet pregnancies of 20 weeks or more was matched for parity and maternal age with two sets of twins delivered in the same year. Primary end points of the analysis were maternal complications and perinatal outcome.
Of the triplets 82% and of the twins 36% were a result of assisted reproduction. Pre-term labor occurred significantly more often in triplet than in twin gestation. Triplets had a significantly lower median birth-weight (1478 vs. 2030 g) and gestational age at delivery (32 vs. 35.5 weeks). The mean neonatal hospital stay was significantly longer in triplets, mainly related to the lower birth-weight, but there was no significant difference between triplets and twins in the incidence of major neonatal complications.
This data of the anticipated perinatal outcome in triplet and twin pregnancies may be used to counsel women with a triplet pregnancy considering selective reduction to twins. All methods of assisted reproduction should aim at prevention of multifetal gestation.
比较三胎妊娠和双胎妊娠的孕产妇及围产期并发症。
在一所大学医院进行病例对照研究。对连续40例孕周达20周及以上的三胎妊娠中的每一例妊娠，按照产次和产妇年龄与同年分娩的两组双胎妊娠进行匹配。分析的主要终点是孕产妇并发症和围产期结局。
三胎妊娠中82%以及双胎妊娠中36%是辅助生殖的结果。三胎妊娠中早产的发生率显著高于双胎妊娠。三胎的出生体重中位数（1478对2030克）和分娩时的孕周（32对35.5周）显著更低。三胎新生儿的平均住院时间显著更长，主要与出生体重较低有关，但三胎和双胎在主要新生儿并发症的发生率上无显著差异。
这些关于三胎妊娠和双胎妊娠预期围产期结局的数据可用于为考虑选择性减胎为双胎的三胎妊娠妇女提供咨询。所有辅助生殖方法都应旨在预防多胎妊娠。
