Cellini M, Baldi A, Possati G L
Università degli Studi di Bologna, Istituto di Clinica Oculistica, Italy.
Int Ophthalmol. 1994;18(6):351-3. doi: 10.1007/BF00930313.
Tissue plasminogen activator (tPA) is able to dissolve any fibrin material that forms in the anterior chamber or vitreous humor. This property has been reported by various experimental studies performed in rabbits. The authors demonstrate the tPA eye drops administered to patients with postoperative hyphema, which did not respond to traditional therapy, gave rapid clearance of the clot. Following its topical administration for the first time in patients, the harmless nature of the drug is emphasized as well as its efficacy. This study indicates the promising features of this drug which deserve further investigation.
组织型纤溶酶原激活剂（tPA）能够溶解在前房或玻璃体液中形成的任何纤维蛋白物质。在兔子身上进行的各种实验研究已经报道了这一特性。作者证明，给传统治疗无效的术后前房积血患者使用tPA眼药水后，血块迅速清除。在首次对患者进行局部给药后，强调了该药物的无害性质及其疗效。这项研究表明了这种药物具有令人期待的特性，值得进一步研究。
