Lutz C, Schweitzer L
Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, KY 40292, USA.
Hear Res. 1995 Apr;84(1-2):12-8. doi: 10.1016/0378-5955(95)00008-r.
Many features of cochlear anatomy vary systematically radially and longitudinally within the organ of Corti. There is limited evidence that along the longitudinal axis of the cochlea the thickness of the subsurface cisternal system in the outer hair cells (OHCs) changes. Similarly a radial gradient may exist. The thickness of the subsurface cisternal system in OHCs was measured in gerbils to determine if there are differences between the three rows of OHCs and in OHCs in different locations along the length of the organ of Corti. The results suggest that there is a longitudinal as well as a radial gradient of subsurface cisternal system thickness. These gradients are the inverse to those for efferent innervation of OHCs. It is possible that these differences may contribute to the increased susceptibility to trauma and ototoxic compounds characteristic of the innermost and basalmost OHCs.
在柯蒂氏器内，耳蜗解剖结构的许多特征在径向和纵向都有系统的变化。有有限的证据表明，沿着耳蜗的纵轴，外毛细胞（OHC）中表面下池系统的厚度会发生变化。同样，可能存在径向梯度。在沙鼠中测量了OHC中表面下池系统的厚度，以确定三排OHC之间以及沿柯蒂氏器长度不同位置的OHC之间是否存在差异。结果表明，表面下池系统厚度存在纵向和径向梯度。这些梯度与OHC传出神经支配的梯度相反。这些差异可能导致最内侧和最基部的OHC对创伤和耳毒性化合物的易感性增加。
