Zhou S, Pickles J O
Department of Physiology and Pharmacology, University of Queensland, Australia.
Hear Res. 1996 Oct;100(1-2):33-40. doi: 10.1016/0378-5955(96)00117-7.
The dimensions of the apical surfaces of hair cells were measured in guinea pigs, aged from 3 weeks before term to 25 weeks after birth. In the basal two-thirds of the cochlea, the apical surfaces of the outer hair cells and their supporting cells changed with age, shrinking in a direction radial across the cochlear duct. There was an associated widening of the angle of the 'V' of the rows of stereocilia. Further apically, between 12 and 16 mm from the base of the cochlea, the outer hair cells and their supporting cells underwent the opposite change, becoming wider in a radial direction with age. The changes were seen before birth and continued for more than 3 weeks after birth. The results suggest that the guinea pig cochlea continues certain developmental processes for a considerable time after birth.
在妊娠期满前3周龄至出生后25周龄的豚鼠中，测量了毛细胞顶表面的尺寸。在耳蜗基部的三分之二区域，外毛细胞及其支持细胞的顶表面随年龄变化，在横跨蜗管的径向方向上缩小。这伴随着静纤毛排的“V”形角度变宽。在更靠近蜗顶的位置，即距耳蜗基部12至16毫米之间，外毛细胞及其支持细胞发生了相反的变化，随着年龄增长在径向方向上变宽。这些变化在出生前就已出现，并在出生后持续超过3周。结果表明，豚鼠耳蜗在出生后相当长的一段时间内仍在继续某些发育过程。
