Yoshikawa K, Kotake S, Ichiishi A, Sasamoto Y, Kosaka S, Matsuda H
Department of Ophthalmology, Hokkaido University School of Medicine, Sapporo.
Jpn J Ophthalmol. 1995;39(1):71-6.
Repository corticosteroid was injected into the posterior sub-Tenon space in 29 cases (39 eyes) of cystoid macular edema (CME) secondary to uveitis. There were 12 cases of Behçet's disease, 7 cases of sarcoidosis, one case of tuberculous uveitis, and 9 cases of etiology unknown uveitis. In some of the patients injections were repeated 2 to 7 times at intervals of more than 2 weeks. Twenty-two of the 39 treated eyes (56.4%) showed visual improvement in at least two lines of visual acuity. Fifteen of the 22 eyes had maintained improved visual acuity over 6 months. Eleven eyes showed no improvement in vision. Most of them already had poor visual acuity (0.2 or less) before the injections. Complications of the treatment included cataract in 6 eyes, glaucoma in one, and blepharoptosis in one. Injection of repository corticosteroids into the posterior sub-Tenon space is of value in the treatment of CME secondary to uveitis. However, we have to beware of the complications of treatment.
将长效皮质类固醇注射到29例（39只眼）葡萄膜炎继发性黄斑囊样水肿（CME）患者的Tenon囊下间隙后部。其中白塞病12例，结节病7例，结核性葡萄膜炎1例，病因不明的葡萄膜炎9例。部分患者每隔2周以上重复注射2至7次。39只治疗眼中的22只（56.4%）视力至少提高了两行。22只眼中的15只在6个月以上保持了视力提高。11只眼视力无改善。其中大多数在注射前视力就已经很差（0.2或更低）。治疗并发症包括6只眼发生白内障，1只眼发生青光眼，1只眼发生上睑下垂。将长效皮质类固醇注射到Tenon囊下间隙后部对治疗葡萄膜炎继发性CME有价值。然而，我们必须警惕治疗并发症。
