Eberhart-Phillips J, Malcolm M, Bandaranayake D, Bates M
Health Communicable Disease Centre, Porirua.
N Z Med J. 1995 Aug 11;108(1005):318-9.
To evaluate the risk of colonisation with N meningitidis among university classroom contacts of a student with invasive meningococcal disease.
Throat cultures were obtained from classmates and faculty exposed to a university student with meningococcal disease. Exposures to the index case were quantified using a questionnaire.
None of the 41 students and staff from whom cultures were obtained showed evidence of colonisation with N meningitidis. The contacts had spent an average of 13.5 h in class with the index case during the 2 days prior to the onset of her illness.
The risk of colonisation with N meningitidis among casual university classroom contacts appears to be low. This study lends support to decisions to withhold chemoprophylaxis in most instances of such contact.
评估侵袭性脑膜炎球菌病学生的大学课堂接触者中脑膜炎奈瑟菌定植的风险。
从接触患脑膜炎球菌病大学生的同学和教职员工处获取咽拭子培养物。使用问卷对与索引病例的接触情况进行量化。
获取培养物的41名学生和工作人员均未显示出脑膜炎奈瑟菌定植的证据。在索引病例发病前2天，接触者与她在课堂上平均共处了13.5小时。
大学课堂上偶然接触者中脑膜炎奈瑟菌定植的风险似乎较低。本研究支持在大多数此类接触情况下不进行化学预防的决定。
